Archive for March, 2012

Medicago Announces 2011 Fourth Quarter and Year-End Financial Results

30 March, 2012

Via Scoop.itVirology News

“2011 was an important year for Medicago as we reported positive clinical results from both our Phase II pandemic H5N1 influenza vaccine clinical trial and Phase I seasonal influenza trial, commenced operations at our 97,000-square-foot facility in North Carolina, and raised over $65 million of equity with investments from Mitsubishi Tanabe Pharma Corporation and other healthcare-focused funds,” said Andy Sheldon, President and Chief Executive Officer of Medicago. “We have already made significant progress in 2012, establishing a strategic alliance with Mitsubishi Tanabe, completing the fourth milestone related to the DARPA project, and moving ahead with our internal rabies vaccine candidate. We expect to continue to take valuable steps forward including the initiation a Phase I clinical trial for a one-dose H5N1 VLP vaccine, the completion of the remaining two DARPA milestones, initiating a US Phase IIa clinical trial for a quadrivalent seasonal flu vaccine, as well as continuing our efforts to execute additional contracts for our VLP technology.”

 

Going green: you know the rest!  B-)

Via www.marketwatch.com

‘Superinfected’ Patients Give Clues to Fighting HIV –Doctors Lounge

30 March, 2012

Via Scoop.itVirology News

A stronger immune response occurs in women who have been infected with two different strains of HIV by two different sexual partners than in women infected with one strain of HIV, a new study finds.This type of dual infection is called HIV “superinfection.”

The finding that a mixture of different HIV strains may be one way to trigger a more powerful immune system antibody response may prove useful in efforts to develop an HIV vaccine in the fight against AIDS, according to the researchers at the Fred Hutchinson Cancer Research Center in Seattle.

 

Via www.doctorslounge.com

American NGOs assail CIA over fake polio drive

29 March, 2012

Via Scoop.itVirology News

ISLAMABAD, March 1: An alliance of about 200 US-based NGOs, many of them working in humanitarian operations in Pakistan, has expressed deep concern over a vaccination campaign carried out in Abbottabad (RT @AnjumKiani: 200 foreign NGO’s working in…

 

It’s bad enough getting people in remote places to participate in especially poliovirus vaccination drives, with disinformation like “it is a plot to make Muslims sterile”.  Now they can legitimately point to the CIA using a fake polio vaccination campaign to smoke out Mr al-Qaeda!

Via www.dawn.com

Wavho’s Story and Message to HIV Pregnant Women – Hope for Limpopo

29 March, 2012

Via Scoop.itVirology News

Whavho tells her own story and discusses the importance of Nevirapine for HIV pregnant women. (Video of the day!

Via hopeforlimpopo.ning.com

Endogenous viruses: insights into viral evolution and impact on host biology

29 March, 2012

Via Scoop.itVirology News

So while you can’t actually get there without a subscription, it’s worth using institutional access to get hold of it….

Nature Reviews Genetics 13, 283-296 (April 2012) | doi:10.1038/nrg3199

 

Recent studies have uncovered myriad viral sequences that are integrated or ‘endogenized’ in the genomes of various eukaryotes. Surprisingly, it appears that not just retroviruses but almost all types of viruses can become endogenous. We review how these genomic ‘fossils’ offer fresh insights into the origin, evolutionary dynamics and structural evolution of viruses, which are giving rise to the burgeoning field of palaeovirology. We also examine the multitude of ways through which endogenous viruses have influenced, for better or worse, the biology of their hosts. We argue that the conflict between hosts and viruses has led to the invention and diversification of molecular arsenals, which, in turn, promote the cellular co-option of endogenous viruses.

“Why all our bird flu research should be published”

29 March, 2012

Via Scoop.itVirology News

Ab Osterhaus: “Our current research has also shown that the mutations that are needed to improve H5N1 transmissibility, already exist in the viruses circulating among poultry in Asia today. This has given us a serious wake-up call, warning us that these viruses could spark a pandemic any time now. By sharing our information with our peers and policy makers in the affected areas, we hope to demonstrate that surveillance activities among animals and humans could and should be cranked up for early warning and increased preparedness.”

 

Yes!!  Like we said, quite a few times….  Thanks, AJC!

Via www.guardian.co.uk

Early temporary treatment for HIV can delay the time to long-term treatment – EurekAlert (press release)

28 March, 2012

Via Scoop.itVirology News

Early temporary treatment for HIV can delay the time to long-term treatmentEurekAlert (press release)A study in this week’s PLoS Medicine suggests that when people are first infected with HIV (primary HIV infection), temporary treatment with antiretroviral…

Via www.eurekalert.org

Sky News: New HPV vaccine to treat infection

28 March, 2012

Via Scoop.itVirology News

He developed a vaccine used worldwide to prevent cervical cancer.

Now the Australian scientist behind that pivotal technology is developing a second vaccine to tackle the human papillomavirus (HPV) which, if successful, could further reduce rates of the aggressive cancer.

Professor Ian Frazer, who was named Australian of the Year in 2006 for developing the groundbreaking vaccine, is working with Brisbane-based biotechnology company Coridon on the new inoculation.

The Gardasil and Cervarix vaccines, which are currently available free for 12 and 13-year-old girls, prevent infection with the cancer-causing HPV virus.

The new vaccine will treat people already infected with the virus, to stop the infection leading to cancer, Prof Frazer said.

Via www.skynews.com.au

HPV Vaccine May Help Women With Cervical Conditions

28 March, 2012

Via Scoop.itVirology News

TUESDAY, March 27 (HealthDay News) — A new study finds that women diagnosed with pre-cancerous cervical conditions after they get the human papillomavirus (HPV) vaccine can still benefit from the shot because it cuts their risk of futureHPV-related cervical disease.”This study helps to clarify the effects of the HPV vaccine and further define its use,” noted one expert, Dr. Elizabeth Poynor, a gynecologic oncologist and pelvic surgeon at Lenox Hill Hospital in New York City.

Via health.yahoo.net

Anti-insect wheat trials underway

28 March, 2012

Via Scoop.itVirology News

The first experiments with plants genetically-modified to repel aphids are under way in the UK.  Wheat has been engineered with a gene from a peppermint plant so that it emits a particular pheromone.

The smell is the alarm signal given off by aphids to warn of an attack by predators.

The researchers hope that this will act as a “no parking sign” to keep the pests at bay without needing insecticide.

This is the first trial of a plant deliberately modified to use pheromones to ward off pests.

The work is taking place at Rothamsted Research, the plant science centre in Hertfordshire

 

Nice place, Rothamsted: and aphids transmit viruses, so it’s right for this site.  Sort of.

Via www.bbc.co.uk