Archive for April 4th, 2012

Opinion: The Risk of Forgoing Vaccines | The Scientist

4 April, 2012

Via Scoop.itVirology News

Opinion: The Risk of Forgoing Vaccines |…

“Given the direct benefit to the individual of immunity against disease, vaccination, is not completely altruistic. However, immunization provides a significant benefit to society. One can liken a human newborn, or a person who cannot get vaccinated, to a vulnerable bird with ticks on the top of its head. As individuals, we cannot fully protect these people from infectious disease, and instead we rely on herd immunity. If society is made up mostly of “suckers” that have expended the energy and cost to get vaccinated, then the vulnerable will be protected due to the absence or reduction of disease transmission. But if a significant percentage of individuals decides against vaccination, for one reason or another, we may lose herd immunity, and infectious disease will spread.”

 

I cannot get over how stupid some people can be.  I certainly won’t let their children play with my children – they might benefit from a herd imunity they are not entitled to.

Via the-scientist.com

ScienceDirect.com – Current Opinion in Virology – Selected approaches for increasing HIV DNA vaccine immunogenicity in vivo

4 April, 2012

Via Scoop.itVirology News

The safety, stability, and ability for repeat homologous vaccination makes the DNA vaccine platform an excellent candidate for an effective HIV-1 vaccine. However, the immunogenicity of early DNA vaccines did not translate from small animal models into larger non-human primates and was markedly lower than viral vectors. In addition to improvements to the DNA vector itself, delivery with electroporation, the inclusion of molecular adjuvants, and heterologous prime-boost strategies have dramatically improved the immunogenicity of DNA vaccines for HIV and currently makes them a leading platform with many areas warranting further research and clinical development.

 

Nice review – even if they don’t mention our extended HIV vaccine group’s work once…ah, the imperialism inherent in HIV vaccine research!

Via www.sciencedirect.com

ProMED mail: RABIES, HUMAN, PRESUMED ABORTIVE 2009 – USA: (TEXAS) UNRESOLVED OUTCOME

4 April, 2012

Via Scoop.itVirology News

Map of the latest alerts on infectious disease around the world…

Houston rabies case poses new questions about age-old illness
————————————————————-
At the US Centers for Disease Control and Prevention [CDC], she’s called the “Texas wild child.” She was a 17-year-old who had run away from home when she walked into a Houston hospital with a fever and puzzling neurological symptoms. Her name is veiled by medical privacy laws, as is the identity of her family back in Missouri; exactly how she was exposed to the virus that sickened her 3 years ago is a mystery. Where she is now, no one seems to know. Her disappearance is part of one of the area’s most intriguing medical mysteries: The CDC says she is the only known person in the US to survive rabies after the onset of clinical symptoms, and without prior vaccination or intensive hospital care.

 

Good account of the current state of rabies therapy – or lack of it.

Image courtesy of Russell Kightley Media

Via www.promedmail.org